Orofacial pain

Orofacial pain

In this work, wind-up and diffuse noxious inhibitory controls of Trigeminal Neurons are studied. Wind-up is a frequency-dependent increase of neuronal response during electrical repetitive noxious stimulation of receptive field.

This study was done during my PhD work under the supervision of Prof Philippe Luccarini, in the laboratory Inserm/ UdA U929. Pr Radhouane Dallel is the Head of the laboratory.

Wind-up of Trigeminal Neurons

Illustration Wind-Up

PhD thesis

Coste J. (2006) Doctorat de Neurosciences | Etude de la fonction et des mécanismes du wind-up des neurones nociceptifs trigéminaux chez le rat : rôle des récepteurs NMDA et des récepteurs NK1

Publications

2008

Coste J.Link to the article
Coste J. et al., Pain 2008
Article
, Voisin DL., Miraucourt LS., Dallel R., Luccarini P. (2008) Dorsal horn NK1-expressing neurons control windup of downstream trigeminal nociceptive neurons. Pain 137(2), 340-51 [HAL Open Access: HAL
hal-01543208

Link to HAL database
] [oDOI ®Open access
Digital Object Identifier
10.1016/j.pain.2007.09.017

Link to Journal website
] | [Cited byPain
Impact factor 2008: 6.030
Quartile Q1: 20/221 (neurosciences)

Citations
ISI Clarivate : 17
Google Scholar
Google Scholar
]| [ PubMed Link to
PubMed
PubMed
] (3/3)

Coste J.Link to the article
Coste J. et al., Cephalalgia 2008
Article
, Voisin DL., Luccarini P., Dallel R. (2008) A role for wind-up in trigeminal sensory processing: intensity coding of nociceptive stimuli in the rat. Cephalalgia 28(6), 631-9 [HAL Open Access: HAL
hal-01543129

Link to HAL database
] [oDOI ®Open access
Digital Object Identifier
10.1111/j.1468-2982.2008.01568.x

Link to Journal website
] | [Cited byCephalalgia
Impact factor 2008: 3.686
Quartile Q2: 61/221 (neurosciences)

Citations
ISI Clarivate : 34
Google Scholar
Google Scholar
]| [ PubMed Link to
PubMed
PubMed
] (2/3)

2004

Woda A.Link to the article
Woda A. et al., European Journal of Neuroscience 2004
Article
, Blanc O., Voisin DL., Coste J., Molat JL., Luccarini P. (2004) Bidirectional modulation of windup by NMDA receptors in the rat spinal trigeminal nucleus. European Journal of Neuroscience 19(8), 2009-16 [HAL Open Access: HAL
hal-01543022

Link to HAL database
] [oDOI ®Open access
Digital Object Identifier
10.1111/j.0953-816X.2004.03328.x

Link to Journal website
] | [Cited byEuropean Journal of Neuroscience
Impact factor 2004: 3.820
Quartile Q1: 42/198 (neurosciences)

Citations
ISI Clarivate : 9
Google Scholar
Google Scholar
]| [ PubMed Link to
PubMed
PubMed
] (1/3)

Communications

2004

Coste J., Luccarini P. (March 2-3, 2004) Mécanismes d’amplification des messages nociceptifs dans le complexe sensitif du trijumeau chez le rat : approche électrophysiologique (Talk) - Journées de l’Ecole Doctorale des Sciences de la Vie et de la Santé de l’Université d’Auvergne (Clermont-Ferrand, France) (2/2)

2003

Coste J., Voisin D. L., Luccarini P., Chalus M., Dallel R. (May 13-16, 2003) L'activation des récepteurs aux neurokinines du sous-noyau caudal du noyau spinal du trijumeau par la substance P facilite le windup des neurones à convergence du sous-noyau oral. (Poster Link to the poster
Communication
) - 6ème Colloque de la Société des Neurosciences (Rouen, France) (1/2)




Diffuse noxious inhibitory controls of Trigeminal Neurons (DNIC)

Illustration CIDN

Communications

2006

Roca-Lapirot O., Coste J., Dallel R., Luccarini P. (November 23, 2006) Diffuse noxious inhibitory controls depend on arterial blood pressure in the anaesthetized rat (Poster) - Journée de la Recherche (Clermont-Ferrand, France) (2/2)

2005

Coste J., Dallel R., Luccarini P. (May 17-20, 2005) Lack of effect of diffuse noxious inhibitory controls triggered by cold on trigeminal convergent neurons in the anaesthetized rat (Poster Link to the poster
Communication
) - 7ème Colloque de la Société des Neurosciences (Lille, France) (1/2)




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